How skin and liver can lead to diagnosis
| Journal | Volume 84 - 2021 |
| Issue | Fasc.4 - Clinical images |
| Author(s) | P. Vande Berg 1, A. Vande Berg 2, E. Harkemanne 3, C. Peeters 3, V. Havelange 4, N. Lanthier 1 |
| Full article |
 PAGES 682-683 VIEW FREE PDF |
| DOI | 10.51821/84.4.024 |
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Affiliations: (1) Service d’Hépato-Gastroentérologie, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium
(2) Service d’Anatomie Pathologique, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium (3) Service de Dermatologie, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium (4) Service d’Hématologie, Cliniques universitaires Saint-Luc, UCLouvain, Brussels, Belgium. |
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A 73-year-old woman was referred by her hematologist for cholestasis of unknown origin. She was recently diagnosed with chronic myelomonocytic leukemia grade 0 in a context of fatigue, night sweats, weight loss and monocytosis. A PET-CT showed hepatosplenomegaly and multiple centimetric adenopathy. The diagnosis was confirmed by a bone marrow aspiration and biopsy. Interestingly, the evolution of the patient is marked by the appearance of cholestasis and an erythematous firm skin nodule of the right forearm. The skin lesion was biopsied to rule out a cutaneous localization of the patient’s known hemopathy. Keywords: cholestasis, skin lesion, systemic mastocytosis, avapritinib. |
| The authors declare that they have no conflict of interest. |
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© Acta Gastro-Enterologica Belgica. PMID 34965056 |
